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Systemic Neurophysiology


Techniques

Calcium imaging

We use calcium imaging from behaving mice to investigate the dynamics of neuronal activity over time. Our goal is to understand how the activation of groups of neurons in various brain regions is regulated over behaviourally relevant timescales.

Selected publications:

Muysers et al., 2025

Muysers et al., 2024

Sylte et al., 2024

 

In vivo electrophysiology

We use large-scale single-unit recordings from behaving mice to explore the dynamics of cortical activities. Specifically, we focus on how neuronal activity patterns are shaped by learning and how these processes evolve over time. 

Selected publications:

Folschweiller & Sauer, 2023

Folschweiller & Sauer, 2022

Sauer et al., 2022

Sauer & Bartos, 2022

Biskamp et al., 2017

Sauer et al., 2015

 

Analysis of network dynamics

 

We use computational tools to extract network activity patterns such as assemblies of coactive neurons from large-scale electrophysiological and imaging data. The goal of this research is to understand how higher-order population activity patterns are organized by ongoing oscillatory activity and behaviour.

Selected papers:

Sylte, Kilias et al., 2025

Sylte et al., 2024

Folschweiller & Sauer, 2022

Sauer & Bartos, 2022

Systemic Neurophysiology

Prof. Dr.
Jonas-Frederic Sauer
  jonas.sauer@
uni-saarland.de
@jf‑sauer.bsky.social

Secretary
Hanling Qin

  +49 6841/ 16-16373
   This email address is being protected from spambots. You need JavaScript enabled to view it.

Universität des Saarlandes
Medizinische Fakultät
Prof. Dr. Jonas-Frederic Sauer
CIPMM | Gebäude 48
D-66421 Homburg (Saar)