Publications
2025 | 2024 | 2023 | 2022 | 2021 | |||||
2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 |
2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 |
Publications 2025
Hemmer, S., Hui, X., Draeger, J., Menges, J., Schwarz, E.C., Wrede, A., Oertel, J., Kaestner, L., Jung, G., Urbschat, S.
"AlkaPhos: a novel fluorescent probe as a potential point-of-care diagnostic tool to estimate recurrence risk of meningiomas"
Neurosurg Rev, 48, 27-XX, (2025), DOI:10.1007/s10143-024-03172-8, Pubmed-ID: 39775316.
Publications 2024
Burgstaller, A., Piernitzki, N., Küchler, N., Koch, M., Kister, T., Eichler, H., Kraus, T., Schwarz, E.C., Dustin, M.L., Lautenschläger, F., Staufer, O.
"Soft Synthetic Cells with Mobile Membrane Ligands for Ex Vivo Expansion of Therapy-Relevant T Cell Phenotypes"
Small, 20, e2401844-XXXXXXXX, (2024), DOI:10.1002/smll.202401844, Pubmed-ID: 38751204.
Zöphel, S., Küchler, N., Jansky, J., Hoxha, C., Schäfer, G., Weise, J.J., Vialle, J., Kaschek, L., Stopper, G., Eichler, H., Yildiz, D., Moter, A., Wendel, P., Ullrich, E., Schormann, C., Rixecker, T., Cetin, O., Neumann, F., Orth, P., Bewarder, M., Hoth, M., Thurner, L., Schwarz, E.C.
"CD16+ as predictive marker for early relapse in aggressive B-NHL/DLBCL patients"
Mol Cancer, 23, 210-XXX, (2024), DOI:10.1186/s12943-024-02123-7, Pubmed-ID: 39342291.
Publications 2023
Thurner, L., Fadle, N., Regitz, E., Roth, S., Cetin, O., Kos, I.A., Hess, S.M., Bein, J., Bohle, R.M., Vornanen, M., Sundström, C., De Leval, L., Tiacci, E., Borchmann, P., Engert, A., Poeschel, V., Held, G., Schwarz, E.C., Neumann, F., Preuss, K., Hoth, M., Küppers, R., Lehman, K., Hansmann, M., Becker, S.L., Bewarder, M., Hartmann, S.
"B-cell receptor reactivity against Rothia mucilaginosa in nodular lymphocyte-predominant Hodgkin lymphoma"
Haematologica, 108, 3347-3358, (2023), DOI:10.3324/haematol.2023.282698, Pubmed-ID: 37139600.
Zöphel, S., Schäfer, G., Nazarieh, M., Konetzki, V., Hoxha, C., Meese, E., Hoth, M., Helms, V., Hamed, M., Schwarz, E.C.
"Identification of molecular candidates which regulate calcium-dependent CD8+ T-cell cytotoxicity"
Mol Immunol, 157, 202-213, (2023), DOI:10.1016/j.molimm.2023.04.002, Pubmed-ID: 37075611.
Publications 2022
Bock, T., Bewarder, M., Cetin, O., Fadle, N., Regitz, E., Schwarz, E.C., Held, J., Roth, S., Lohse, S., Pfuhl, T., Wagener, R., Smola, S., Becker, S.L., Bohle, R.M., Trümper, L., Siebert, R., Hansmann, M., Pfreundschuh, M., Drexler, H.G., Hoth, M., Kubuschok, B., Roemer, K., Preuss, K., Hartmann, S., Thurner, L.
"B-cell receptors of EBV-negative Burkitt lymphoma bind modified isoforms of autoantigens"
EJHaem, 3, 739-747, (2022), DOI:10.1002/jha2.475, Pubmed-ID: 36051037.
Friedmann, K. S. , Kaschek, L., Knörck, A., Cappello, S., Lünsmann, N., Küchler, N., Hoxha, C., Schäfer, G., Iden, S., Bogeski, I., Kummerow, C., Schwarz, E.C., Hoth, M.
"Interdependence of sequential cytotoxic T lymphocyte and natural killer cell cytotoxicity against melanoma cells"
J Physiol, 600, 5027-5054, (2022), DOI:10.1113/JP283667, Pubmed-ID: 36226443.
Knörck, A., Schäfer, G., Alansary, D., Richter, J., Thurner, L., Hoth, M., Schwarz, E.C.
"Cytotoxic Efficiency of Human CD8+ T Cell Memory Subtypes"
Front Immunol, 13, 838484-XXXXXX, (2022), DOI:10.3389/fimmu.2022.838484, Pubmed-ID: 35493468.
Yang, W., Denger, A., Diener, C., Küppers, F., Soriano-Baguet, L., Schäfer, G., Yanamandra, A.K., Zhao, R., Knörck, A., Schwarz, E.C., Hart, M., Lammert, F., Roma, L.P., Brenner, D., Christidis, G., Helms, V., Meese, E., Hoth, M., Qu, B.
"Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand"
Front Immunol, 13, 831680-XXXXXX, (2022), DOI:10.3389/fimmu.2022.831680, Pubmed-ID: 35265081.
Publications 2021
Zhao, R., Zhou, X., Khan, E.S., Alansary, D., Friedmann, K.S., Yang, W., Schwarz, E.C., Del Campo, A., Hoth, M., Qu, B.
"Targeting the Microtubule-Network Rescues CTL Killing Efficiency in Dense 3D Matrices"
Front Immunol, 12, 729820-XXXXXX, (2021), DOI:10.3389/fimmu.2021.729820, Pubmed-ID: 34484240.
Zhu, J., Yang, W., Zhou, X., Zöphel, D., Soriano-Baguet, L., Dolgener, D., Carlein, C., Hof, C., Zhao, R., Ye, S., Schwarz, E.C., Brenner, D., Prates Roma, L., Qu, B.
"High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity"
Front Immunol, 12, 689337-XXXXXX, (2021), DOI:10.3389/fimmu.2021.689337, Pubmed-ID: 34248978.
Publications 2020
Zou, H., Yang, W., Schwär, G., Zhao, R., Alansary, D., Yin, D., Schwarz, E.C., Niemeyer, B.A., Qu, B.
"High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation"
Eur J Immunol, 50, 2095-2098, (2020), DOI:10.1002/eji.202048577, Pubmed-ID: 32697355.
Zhou, Y., Zhao, R., Schwarz, E.C., Akbar, R., Kaba, M., Pattu, V., Helms, V., Rieger, H., Nunes-Hasler, P., Qu, B.
"Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T Cells"
J Immunol, 205, 2988-3000, (2020), DOI:10.4049/jimmunol.2000195, Pubmed-ID: 33106338.
Publications 2019
Knowles, L. M. , Kagiri, D., Bernard, M., Schwarz, E.C., Eichler, H., Pilch, J.
"Macrophage Polarization is Deregulated in Haemophilia"
Thromb Haemost, 119, 234-245, (2019), DOI:10.1055/s-0038-1676796, Pubmed-ID: 30650445.
Leisegang, M. S. , Gu, L., Preussner, J., Günther, S., Hitzel, J., Ratiu, C., Weigert, A., Chen, W., Schwarz, E.C., Looso, M., Fork, C., Brandes, R.P.
"The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G"
FEBS Lett, 593, 487-498, (2019), DOI:10.1002/1873-3468.13337, Pubmed-ID: 30758047.
Hart, M., Walch-Rückheim, B., Friedmann, K.S., Rheinheimer, S., Tänzer, T., Glombitza, B., Sester, M., Lenhof, H., Hoth, M., Schwarz, E.C., Keller, A., Meese, E.
"miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling"
Cell Death Dis, 10, 46-XX, (2019), DOI:10.1038/s41419-018-1295-1, Pubmed-ID: 30718475.
Publications 2018
Knörck, A., Marx, S., Friedmann, K.S., Zöphel, S., Lieblang, L., Hässig, C., Müller, I., Pilch, J., Sester, U., Hoth, M., Eichler, H., Sester, M., Schwarz, E.C.
"Quantity, quality, and functionality of peripheral blood cells derived from residual blood of different apheresis kits"
Transfusion, 58, 1516-1526, (2018), DOI:10.1111/trf.14616, Pubmed-ID: 29732580.
Zhou, X., Friedmann, K.S., Lyrmann, H., Zhou, Y., Schoppmeyer, R., Knörck, A., Mang, S., Hoxha, C., Angenendt, A., Backes, C.S., Mangerich, C., Zhao, R., Cappello, S., Schwär, G., Hässig, C., Neef, M., Bufe, B., Zufall, F., Kruse, K., Niemeyer, B.A., Lis, A., Qu, B., Kummerow, C., Schwarz, E.C., Hoth, M.
"A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity"
J Physiol, 596, 2681-2698, (2018), DOI:10.1113/JP274964, Pubmed-ID: 29368348.
Publications 2017
Schoppmeyer, R., Zhao, R., Cheng, H., Hamed, M., Liu, C., Zhou, X., Schwarz, E.C., Zhou, Y., Knörck, A., Schwär, G., Ji, S., Liu, L., Long, J., Helms, V., Hoth, M., Yu, X., Qu, B.
"Human profilin 1 is a negative regulator of CTL mediated cell-killing and migration"
Eur J Immunol, 47, 1562-1572, (2017), DOI:10.1002/eji.201747124, Pubmed-ID: 28688208.
Zhou, X., Zhao, R., Schwarz, K., Mangeat, M., Schwarz, E.C., Hamed, M., Bogeski, I., Helms, V., Rieger, H., Qu, B.
"Bystander cells enhance NK cytotoxic efficiency by reducing search time"
Sci Rep, 7, 44357-XXXXX, (2017), DOI:10.1038/srep44357, Pubmed-ID: 28287155.
Eisenbeis, J., Peisker, H., Backes, C.S., Bur, S., Hölters, S., Thewes, N., Greiner, M., Junker, C., Schwarz, E.C., Hoth, M., Junker, K., Preissner, K.T., Jacobs, K., Herrmann, M., Bischoff, M.
"The extracellular adherence protein (Eap) of Staphylococcus aureus acts as a proliferation and migration repressing factor that alters the cell morphology of keratinocytes"
Int J Med Microbiol, 307, 116-125, (2017), DOI:10.1016/j.ijmm.2017.01.002, Pubmed-ID: 28117265.
Publications 2016
Bhat, S. S. , Friedmann, K.S., Knörck, A., Hoxha, C., Leidinger, P., Backes, C., Meese, E., Keller, A., Rettig, J., Hoth, M., Qu, B., Schwarz, E.C.
"Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes"
Biochim Biophys Acta, 1863, 1653-1664, (2016), DOI:10.1016/j.bbamcr.2016.04.014, Pubmed-ID: 27094127.
Saul, S., Gibhardt, C.S., Schmidt, B., Lis, A., Pasieka, B., Conrad, D., Jung, P., Gaupp, R., Wonnenberg, B., Diler, E., Stanisz, H., Vogt, T., Schwarz, E.C., Bischoff, M., Herrmann, M., Tschernig, T., Kappl, R., Rieger, H., Niemeyer, B.A., Bogeski, I.
"A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels"
Sci Signal, 9, ra26-XXXX, (2016), DOI:10.1126/scisignal.aaf1639, Pubmed-ID: 26956485.
Schwarz, E. C. , Backes, C., Knörck, A., Ludwig, N., Leidinger, P., Hoxha, C., Schwär, G., Grossmann, T., Müller, S.C., Hart, M., Haas, J., Galata, V., Müller, I., Fehlmann, T., Eichler, H., Franke, A., Meder, B., Meese, E., Hoth, M., Keller, A.
"Deep characterization of blood cell miRNomes by NGS"
Cell Mol Life Sci, 73, 3169-3181, (2016), DOI:10.1007/s00018-016-2154-9, Pubmed-ID: 26874686.
Publications 2014
Kummerow, C., Schwarz, E.C., Bufe, B., Zufall, F., Hoth, M., Qu, B.
"A simple, economic, time-resolved killing assay"
Eur J Immunol, 44, 1870-1872, (2014), DOI:10.1002/eji.201444518, Pubmed-ID: 24599783.
Saul, S., Stanisz, H., Backes, C.S., Schwarz, E.C., Hoth, M.
"How ORAI and TRP channels interfere with each other: interaction models and examples from the immune system and the skin"
Eur J Pharmacol, 739, 49-59, (2014), DOI:10.1016/j.ejphar.2013.10.071, Pubmed-ID: 24291108.
Halimani, M., Pattu, V., Marshall, M.R., Chang, H.F., Matti, U., Jung, M., Becherer, U., Krause, E., Hoth, M., Schwarz, E.C., Rettig, J.
"Syntaxin11 serves as a t-SNARE for the fusion of lytic granules in human cytotoxic T lymphocytes"
Eur J Immunol, 44, 573-584, (2014), DOI:10.1002/eji.201344011, Pubmed-ID: 24227526.
Publications 2013
Schwarz, E. C. , Qu, B., Hoth, M.
"Calcium, cancer and killing: the role of calcium in killing cancer cells by cytotoxic T lymphocytes and natural killer cells"
Biochim Biophys Acta, 1833, 1603-1611, (2013), DOI:10.1016/j.bbamcr.2012.11.016, Pubmed-ID: 23220009.
Publications 2012
Stanisz, H., Stark, A., Kilch, T., Schwarz, E.C., Müller, C.S.L., Peinelt, C., Hoth, M., Niemeyer, B.A., Vogt, T., Bogeski, I.
"ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes"
J Invest Dermatol, 132, 1443-1451, (2012), DOI:10.1038/jid.2011.478, Pubmed-ID: 22318387.
Pattu, V., Qu, B., Schwarz, E.C., Strauss, B., Weins, L., Bhat, S.S., Halimani, M., Marshall, M., Rettig, J., Hoth, M.
"SNARE protein expression and localization in human cytotoxic T lymphocytes"
Eur J Immunol, 42, 470-475, (2012), DOI:10.1002/eji.201141915, Pubmed-ID: 22120889.
Publications 2011
Pattu, V., Qu, B., Marshall, M., Becherer, U., Junker, C., Matti, U., Schwarz, E.C., Krause, E., Hoth, M., Rettig, J.
"Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes"
Traffic, 12, 890-901, (2011), DOI:10.1111/j.1600-0854.2011.01193.x, Pubmed-ID: 21438968.
Qu, B., Pattu, V., Junker, C., Schwarz, E.C., Bhat, S.S., Kummerow, C., Marshall, M., Matti, U., Neumann, F., Pfreundschuh, M., Becherer, U., Rieger, H., Rettig, J., Hoth, M.
"Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes"
J Immunol, 186, 6894-6904, (2011), DOI:10.4049/jimmunol.1003471, Pubmed-ID: 21562157.
Qu, B., Al-Ansary, D., Kummerow, C., Hoth, M., Schwarz, E.C.
"ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance"
Cell Calcium, 50, 261-269, (2011), DOI:10.1016/j.ceca.2011.05.015, Pubmed-ID: 21665274.
Wenning, A. S. , Neblung, K., Strauss, B., Wolfs, M., Sappok, A., Hoth, M., Schwarz, E.C.
"TRP expression pattern and the functional importance of TRPC3 in primary human T-cells"
Biochim Biophys Acta, 1813, 412-423, (2011), DOI:10.1016/j.bbamcr.2010.12.022, Pubmed-ID: 21215279.
Publications 2010
Dieckmann, R., von Heyden, Y., Kistler, C., Gopaldass, N., Hausherr, S., Crawley, S.W., Schwarz, E.C., Diensthuber, R.P., Côté, G.P., Tsiavaliaris, G., Soldati, T.
"A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiency"
Mol Biol Cell, 21, 1505-1518, (2010), DOI:10.1091/mbc.e09-06-0485, Pubmed-ID: 20200225.
Bogeski, I., Kummerow, C., Al-Ansary, D., Schwarz, E.C., Koehler, R., Kozai, D., Takahashi, N., Peinelt, C., Griesemer, D., Bozem, M., Mori, Y., Hoth, M., Niemeyer, B.A.
"Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling"
Sci Signal, 3, ra24-XXXX, (2010), DOI:10.1126/scisignal.2000672, Pubmed-ID: 20354224.
Thiel, M., Wolfs, M., Bauer, S., Wenning, A.S., Burckhart, T., Schwarz, E.C., Scott, A.M., Renner, C., Hoth, M.
"Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry"
Immunology, 129, 28-40, (2010), DOI:10.1111/j.1365-2567.2009.03155.x, Pubmed-ID: 19824921.
Publications 2007
Schwarz, E. C. , Kummerow, C., Wenning, A.S., Wagner, K., Sappok, A., Waggershauser, K., Griesemer, D., Strauss, B., Wolfs, M., Quintana, A., Hoth, M.
"Calcium dependence of T cell proliferation following focal stimulation"
Eur J Immunol, 37, 2723-2733, (2007), DOI:10.1002/eji.200737039, Pubmed-ID: 17899547.
Quintana, A., Schwindling, C., Wenning, A.S., Becherer, U., Rettig, J., Schwarz, E.C., Hoth, M.
"T cell activation requires mitochondrial translocation to the immunological synapse"
Proc Natl Acad Sci U S A, 104, 14418-14423, (2007), DOI:10.1073/pnas.0703126104, Pubmed-ID: 17726106.
Schwarz, E. C. , Wolfs, M.J., Tonner, S., Wenning, A.S., Quintana, A., Griesemer, D., Hoth, M.
"TRP channels in lymphocytes"
Handb Exp Pharmacol, , (2007), DOI:10.1007/978-3-540-34891-7_26, Pubmed-ID: 17217072.
Publications 2006
Quintana, A., Schwarz, E.C., Schwindling, C., Lipp, P., Kaestner, L., Hoth, M.
"Sustained activity of calcium release-activated calcium channels requires translocation of mitochondria to the plasma membrane"
J Biol Chem, 281, 40302-40309, (2006), DOI:10.1074/jbc.M607896200, Pubmed-ID: 17056596.
Griesemer, D., Löffler, B., Kummerow, C., Quintana, A., Schwarz, E.C., Hoth, M.
"Calcium release-activated calcium channels as signal transducers in T-cells"
Signal Transduction, 6, 233-239, (2006), DOI:10.1002/sita.200600092.
Schwarz, E. C. , Wissenbach, U., Niemeyer, B.A., Strauss, B., Philipp, S.E., Flockerzi, V., Hoth, M.
"TRPV6 potentiates calcium-dependent cell proliferation"
Cell Calcium, 39, 163-173, (2006), DOI:10.1016/j.ceca.2005.10.006, Pubmed-ID: 16356545.
Publications 2005
Quintana, A., Griesemer, D., Schwarz, E.C., Hoth, M.
"Calcium-dependent activation of T-lymphocytes"
Pflugers Arch, 450, 1-12, (2005), DOI:10.1007/s00424-004-1364-4, Pubmed-ID: 15806400.
Publications 2004
Zitt, C., Strauss, B., Schwarz, E.C., Spaeth, N., Rast, G., Hatzelmann, A., Hoth, M.
"Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2"
J Biol Chem, 279, 12427-12437, (2004), DOI:10.1074/jbc.M309297200, Pubmed-ID: 14718545.
Schwarz, A., Tutsch, E., Ludwig, B., Schwarz, E.C., Stallmach, A., Hoth, M.
"Ca2+ signaling in identified T-lymphocytes from human intestinal mucosa. Relation to hyporeactivity, proliferation, and inflammatory bowel disease"
J Biol Chem, 279, 5641-5647, (2004), DOI:10.1074/jbc.M309317200, Pubmed-ID: 14585840.