Publications
2023 | 2022 | 2021 | |||||||
2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 |
2010 |
Publications 2023
Struckmeier, A., Radermacher, A., Fehrenz, M., Bellin, T., Alansary, D., Wartenberg, P., Boehm, U., Wagner, M., Scheller, A., Hess, J., Moratin, J., Freudlsperger, C., Hoffmann, J., Thurner, L., Roemer, K., Freier, K., Horn, D.
"IDO1 is highly expressed in macrophages of patients in advanced tumour stages of oral squamous cell carcinoma"
J Cancer Res Clin Oncol, 149, 3623-3635, (2023), DOI:10.1007/s00432-022-04277-7, Pubmed-ID: 35963900.
Publications 2022
Wrublewsky, S., Speer, T., Nalbach, L., Boewe, A.S., Pack, M., Alansary, D., Roma, L.P., Hoffmann, M.D.A., Schmitt, B.M., Weinzierl, A., Menger, M.D., Laschke, M.W., Ampofo, E.
"Targeting Pancreatic Islet NLRP3 Improves Islet Graft Revascularization"
Diabetes, 71, 1706-1720, (2022), DOI:10.2337/db21-0851, Pubmed-ID: 35622000.
Tandl, D., Sponagel, T., Alansary, D., Fuck, S., Smit, T., Hehlgans, S., Jakob, B., Fournier, C., Niemeyer, B.A., Rödel, F., Roth, B., Moroni, A., Thiel, G.
"X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca2+ entry and NFAT activation"
J Gen Physiol, 154, e202112865, (2022), DOI:10.1085/jgp.202112865, Pubmed-ID: 35416945.
Knörck, A., Schäfer, G., Alansary, D., Richter, J., Thurner, L., Hoth, M., Schwarz, E.C.
"Cytotoxic Efficiency of Human CD8+ T Cell Memory Subtypes"
Front Immunol, 13, 838484-XXXXXX, (2022), DOI:10.3389/fimmu.2022.838484, Pubmed-ID: 35493468.
Knapp, M. L. , Alansary, D., Poth, V., Förderer, K., Sommer, F., Zimmer, D., Schwarz, Y., Künzel, N., Kless, A., Machaca, K., Helms, V., Mühlhaus, T., Schroda, M., Lis, A., Niemeyer, B.A.
"A longer isoform of Stim1 is a negative SOCE regulator but increases cAMP-modulated NFAT signaling"
EMBO Rep, 23, e53135-XXXXXX, (2022), DOI:10.15252/embr.202153135, Pubmed-ID: 34942054.
Publications 2021
Schunk, S. J. , Triem, S., Schmit, D., Zewinger, S., Sarakpi, T., Becker, E., Hütter, G., Wrublewsky, S., Küting, F., Hohl, M., Alansary, D., Prates Roma, L., Lipp, P., Möllmann, J., Lehrke, M., Laschke, M.W., Menger, M.D., Kramann, R., Boor, P., Jahnen-Dechent, W., März, W., Böhm, M., Laufs, U., Niemeyer, B.A., Fliser, D., Ampofo, E., Speer, T.
"Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease"
Circulation, 144, 893-908, (2021), DOI:10.1161/CIRCULATIONAHA.121.053547, Pubmed-ID: 34192892.
Zhao, R., Zhou, X., Khan, E.S., Alansary, D., Friedmann, K.S., Yang, W., Schwarz, E.C., Del Campo, A., Hoth, M., Qu, B.
"Targeting the Microtubule-Network Rescues CTL Killing Efficiency in Dense 3D Matrices"
Front Immunol, 12, 729820-XXXXXX, (2021), DOI:10.3389/fimmu.2021.729820, Pubmed-ID: 34484240.
Peckys, D. B. , Gaa, D., Alansary, D., Niemeyer, B.A., Jonge, N.d.
"Supra-Molecular Assemblies of ORAI1 at Rest Precede Local Accumulation into Puncta after Activation"
Int J Mol Sci, 22, 799, (2021), DOI:10.3390/ijms22020799, Pubmed-ID: 33466866.
Publications 2020
Zou, H., Yang, W., Schwär, G., Zhao, R., Alansary, D., Yin, D., Schwarz, E.C., Niemeyer, B.A., Qu, B.
"High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation"
Eur J Immunol, 50, 2095-2098, (2020), DOI:10.1002/eji.202048577, Pubmed-ID: 32697355.
Gibhardt, C. S. , Cappello, S., Bhardwaj, R., Schober, R., Kirsch, S.A., Bonilla Del Rio, Z., Gahbauer, S., Bochicchio, A., Sumanska, M., Ickes, C., Stejerean-Todoran, I., Mitkovski, M., Alansary, D., Zhang, X., Revazian, A., Fahrner, M., Lunz, V., Frischauf, I., Luo, T., Ezerina, D., Messens, J., Belousov, V.V., Hoth, M., Böckmann, R.A., Hediger, M.A., Schindl, R., Bogeski, I.
"Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry"
Cell Rep, 33, 108292-XXXXXX, (2020), DOI:10.1016/j.celrep.2020.108292, Pubmed-ID: 33086068.
Alansary, D., Peckys, D.B., Niemeyer, B.A., de Jonge, N.
"Detecting single ORAI1 proteins within the plasma membrane reveals higher-order channel complexes"
J Cell Sci, 133, jcs240358, (2020), DOI:10.1242/jcs.240358, Pubmed-ID: 31822631.
Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Triem, S., Klug, M., Schunk, S.J., Schmit, D., Kramann, R., Körbel, C., Ampofo, E., Laschke, M.W., Selejan, S., Paschen, A., Herter, T., Schuster, S., Silbernagel, G., Sester, M., Sester, U., Aßmann, G., Bals, R., Kostner, G., Jahnen-Dechent, W., Menger, M.D., Rohrer, L., März, W., Böhm, M., Jankowski, J., Kopf, M., Latz, E., Niemeyer, B.A., Fliser, D., Laufs, U., Speer, T.
"Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation"
Nat Immunol, 21, 30-41, (2020), DOI:10.1038/s41590-019-0548-1, Pubmed-ID: 31819254.
Publications 2019
Schmidt, B., Alansary, D., Bogeski, I., Niemeyer, B.A., Rieger, H.
"Reaction-diffusion model for STIM-ORAI interaction: The role of ROS and mutations"
J Theor Biol, 470, 64-75, (2019), DOI:10.1016/j.jtbi.2019.02.010, Pubmed-ID: 30853394.
Alansary, D., Niemeyer, B.A.
"Stepping out of the shadow: STIM2 promotes IL-3-induced cytokine release"
Sci Signal, 12, eaax0210, (2019), DOI:10.1126/scisignal.aax0210, Pubmed-ID: 30967511.
Publications 2018
Riva, B., Griglio, A., Serafini, M., Cordero-Sanchez, C., Aprile, S., Di Paola, R., Gugliandolo, E., Alansary, D., Biocotino, I., Lim, D., Grosa, G., Galli, U., Niemeyer, B., Sorba, G., Canonico, P.L., Cuzzocrea, S., Genazzani, A.A., Pirali, T.
"Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis"
J Med Chem, 61, 9756-9783, (2018), DOI:10.1021/acs.jmedchem.8b01512, Pubmed-ID: 30347159.
Diener, C., Hart, M., Alansary, D., Poth, V., Walch-Rückheim, B., Menegatti, J., Grässer, F., Fehlmann, T., Rheinheimer, S., Niemeyer, B.A., Lenhof, H., Keller, A., Meese, E.
"Modulation of intracellular calcium signaling by microRNA-34a-5p"
Cell Death Dis, 9, 1008-XXXX, (2018), DOI:10.1038/s41419-018-1050-7, Pubmed-ID: 30262862.
Bunse, L., Pusch, S., Bunse, T., Sahm, F., Sanghvi, K., Friedrich, M., Alansary, D., Sonner, J.K., Green, E., Deumelandt, K., Kilian, M., Neftel, C., Uhlig, S., Kessler, T., von Landenberg, A., Berghoff, A.S., Marsh, K., Steadman, M., Zhu, D., Nicolay, B., Wiestler, B., Breckwoldt, M.O., Al-Ali, R., Karcher-Bausch, S., Bozza, M., Oezen, I., Kramer, M., Meyer, J., Habel, A., Eisel, J., Poschet, G., Weller, M., Preusser, M., Nadji-Ohl, M., Thon, N., Burger, M.C., Harter, P.N., Ratliff, M., Harbottle, R., Benner, A., Schrimpf, D., Okun, J., Herold-Mende, C., Turcan, S., Kaulfuss, S., Hess-Stumpp, H., Bieback, K., Cahill, D.P., Plate, K.H., Hänggi, D., Dorsch, M., Suvà, M.L., Niemeyer, B.A., von Deimling, A., Wick, W., Platten, M.
"Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate"
Nat Med, 24, 1192-1203, (2018), DOI:10.1038/s41591-018-0095-6, Pubmed-ID: 29988124.
Kircher, S., Merino-Wong, M., Niemeyer, B.A., Alansary, D.
"Profiling calcium signals of in vitro polarized human effector CD4+ T cells"
Biochim Biophys Acta Mol Cell Res, 1865, 932-943, (2018), DOI:10.1016/j.bbamcr.2018.04.001, Pubmed-ID: 29626493.
Publications 2016
Alansary, D., Schmidt, B., Dörr, K., Bogeski, I., Rieger, H., Kless, A., Niemeyer, B.A.
"Thiol dependent intramolecular locking of Orai1 channels"
Sci Rep, 6, 33347-XXXXX, (2016), DOI:10.1038/srep33347, Pubmed-ID: 27624281.
Peckys, D. B. , Alansary, D., Niemeyer, B.A., de Jonge, N.
"Visualizing Quantum Dot Labeled ORAI1 Proteins in Intact Cells Via Correlative Light and Electron Microscopy"
Microsc Microanal, 22, 902-912, (2016), DOI:10.1017/S1431927616011491, Pubmed-ID: 27515473.
Dörr, K., Kilch, T., Kappel, S., Alansary, D., Schwär, G., Niemeyer, B.A., Peinelt, C.
"Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry"
Sci Signal, 9, ra25-XXXX, (2016), DOI:10.1126/scisignal.aaa9913, Pubmed-ID: 26956484.
Publications 2015
Miederer, A., Alansary, D., Schwär, G., Lee, P., Jung, M., Helms, V., Niemeyer, B.A.
"A STIM2 splice variant negatively regulates store-operated calcium entry"
Nat Commun, 6, 6899-XXXX, (2015), DOI:10.1038/ncomms7899, Pubmed-ID: 25896806.
Alansary, D., Bogeski, I., Niemeyer, B.A.
"Facilitation of Orai3 targeting and store-operated function by Orai1"
Biochim Biophys Acta, 1853, 1541-1550, (2015), DOI:10.1016/j.bbamcr.2015.03.007, Pubmed-ID: 25791427.
Publications 2014
Alansary, D., Kilch, T., Holzmann, C., Peinelt, C., Hoth, M., Lis, A.
"Patch-clamp measurement of ICRAC and ORAI channel activity"
Cold Spring Harb Protoc, 2014, 602-607, (2014), DOI:10.1101/pdb.top066795, Pubmed-ID: 24890214.
Alansary, D., Kilch, T., Holzmann, C., Peinelt, C., Hoth, M., Lis, A.
"The minimal requirements to use calcium imaging to analyze ICRAC"
Cold Spring Harb Protoc, 2014, 638-642, (2014), DOI:10.1101/pdb.prot073262, Pubmed-ID: 24890204.
Alansary, D., Kilch, T., Holzmann, C., Peinelt, C., Hoth, M., Lis, A.
"Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique"
Cold Spring Harb Protoc, 2014, 630-637, (2014), DOI:10.1101/pdb.prot073254, Pubmed-ID: 24890203.
Publications 2013
Kilch, T., Alansary, D., Peglow, M., Dörr, K., Rychkov, G., Rieger, H., Peinelt, C., Niemeyer, B.A.
"Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1"
J Biol Chem, 288, 1653-1664, (2013), DOI:10.1074/jbc.M112.417246, Pubmed-ID: 23212906.
Publications 2011
Quintana, A., Pasche, M., Junker, C., Al-Ansary, D., Rieger, H., Kummerow, C., Nuñez, L., Villalobos, C., Meraner, P., Becherer, U., Rettig, J., Niemeyer, B.A., Hoth, M.
"Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation"
EMBO J, 30, 3895-3912, (2011), DOI:10.1038/emboj.2011.289, Pubmed-ID: 21847095.
Qu, B., Al-Ansary, D., Kummerow, C., Hoth, M., Schwarz, E.C.
"ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance"
Cell Calcium, 50, 261-269, (2011), DOI:10.1016/j.ceca.2011.05.015, Pubmed-ID: 21665274.
Publications 2010
Bogeski, I., Al-Ansary, D., Qu, B., Niemeyer, B.A., Hoth, M., Peinelt, C.
"Pharmacology of ORAI channels as a tool to understand their physiological functions"
Expert Rev Clin Pharmacol, 3, 291-303, (2010), DOI:10.1586/ecp.10.23, Pubmed-ID: 22111611.
Bogeski, I., Kummerow, C., Al-Ansary, D., Schwarz, E.C., Koehler, R., Kozai, D., Takahashi, N., Peinelt, C., Griesemer, D., Bozem, M., Mori, Y., Hoth, M., Niemeyer, B.A.
"Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling"
Sci Signal, 3, ra24-XXXX, (2010), DOI:10.1126/scisignal.2000672, Pubmed-ID: 20354224.
Al-Ansary, D., Bogeski, I., Disteldorf, B.M.J., Becherer, U., Niemeyer, B.A.
"ATP modulates Ca2+ uptake by TRPV6 and is counteracted by isoform-specific phosphorylation"
FASEB J, 24, 425-435, (2010), DOI:10.1096/fj.09-141481, Pubmed-ID: 19805577.