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Cellular Neurophysiology

High-resolution electrophysiology


Whole-cell, perforated patch, cell-attached, voltage-clamp, current-clamp, membrane capacitance, carbon fiber amperometry, flash photolysis, loose-patch, field potential recordings

Electron microscopy


cryo-EM, REM, CLEM (correlative light and electron microscopy)

Transgenic mouse models

CRISPR/Cas; global or tissue-specific Knock-in and Knock-out

Collaborative studies include: in situ hybridization, single cell/small tissue isolation and gene analysis


Cell culture

Neurons from various brain regions, chromaffin cells, cytotoxic T lymphocytes, astrocytes, BHK cells, 293 cells and many more 


Flow cytometry

FACS AriaIII, 11 colors, sorting and analyses 


in vivo microscopy

2-photon in vivo microscopy of graft rejection inside the anterior chamber of the eye

High-resolution live cell and tissue imaging

Calcium imaging, stimulated emission depletion (STED) microscopy, total internal reflection fluorescence microscopy (TIRFM), particle tracking, confocal microscopy (LSM780), structured illumination microscopy (SIM), single molecule fluorescence (PALM, STORM)





provisional management:

Prof. Dr. Dieter Bruns


Bernadette Schwarz

  +49 6841/16-16400
  +49 6841/16-16402

Cellular Neurophysiology
Saarland University
CIPMM | Building 48
D-66421 Homburg